Freeze-Dried Ham Promotes Azoxymethane-Induced Mucin-Depleted Foci and Aberrant Crypt Foci in Rat Colon
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منابع مشابه
Freeze-dried ham promotes azoxymethane-induced mucin-depleted foci and aberrant crypt foci in rat colon.
Processed and red meat consumption is associated with the risk of colorectal cancer. Meta-analyses have suggested that the risk associated with processed meat is higher. Most processed meats are cured and cooked, which leads to formation of free nitrosyl heme. We speculated that free nitrosyl heme is more toxic than native myoglobin. The promoting effect of a freeze-dried, cooked, cured ham die...
متن کاملBeef meat and blood sausage promote azoxymethane - induced 1 mucin - depleted foci and aberrant crypt foci in rat colons
16 dimethyldiazol-2-yl)-2,5 diphenyl tetrazolium bromid, TBARS: thiobarbituric acid reactive 17 substances 18 4-Data were presented at the 4 th Abstract 23 24 Red meat is associated with colon cancer risk. Puzzlingly, meat does not promote 25 carcinogenesis in rodent studies. However, we demonstrated previously that dietary heme 26 promotes aberrant crypt foci (ACF), in rats given a low-calcium...
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BACKGROUND Flat aberrant crypt foci (flat ACF) and mucin-depleted foci (MDF) are preneoplastic lesions identified in the colon of carcinogen-treated rodents stained with methylene blue (MB) and high iron diamine-alcian blue (HID-AB), respectively. The correspondence between flat ACF and MDF in the same colon of Min mice treated with azoxymethane (AOM) and of F344 rats treated with 1,2-dimethylh...
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In this work, microscopic and histological studies suggest that Strobilanthes crispus ethanol extract reduce azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) in rats. S. crispus is considered a traditional medicine and used as an antioxidant. Its leaf contains a large amount of phenolic compounds to which its radical scavenging role is attributed and enhance its ability to eradicate...
متن کاملDietary polyamines promote the growth of azoxymethane-induced aberrant crypt foci in rat colon.
We have examined whether dietary polyamines influence the formation and initial growth of azoxymethane (AOM)-induced aberrant crypt foci (ACF) in rat colon. Effects of a combination of dietary polyamines at three dose levels (putrescine: 50, 280, 740 nmol/g; spermidine: 10, 261, 763 nmol/g; spermine: 1, 31, 91 nmol/g) in the polyamine-poor AIN-76A diet were studied in animals in two different e...
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ژورنال
عنوان ژورنال: Nutrition and Cancer
سال: 2010
ISSN: 0163-5581,1532-7914
DOI: 10.1080/01635580903532408